Minia UniversityJournal of Modern Research2636-39091120190701Antibacterial and Urease Inhibitory activity of New Piperazinyl N-4 Functionalized Ciprofloxacin-oxadiazoles174136110.21608/jmr.2019.12650.1001ENMohamed A.A. Abdel-AalDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, EgyptSalah A.Abdel-AzizDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, EgyptMontaser Sh. A.ShaykoonDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut 71524, EgyptMamdouh F. A.MohamedDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Sohag University, Sohag 82524, EgyptGamal El-Din A.A.Abuo-RahmaDepartment of Medicinal Chemistry, Faculty of Pharmacy, Minia University, 61519 Minia, EgyptJournal Article20190509This research includes design of new ciprofloxacin bearing oxadiazole at the N-4 piperazinyl for the purpose of having urease inhibitory activity as well as antibacterial activity. Hence, a group of new N-4 piperazinyl oxdiazole derivatives of ciprofloxacin was prepared and characterized using different spectroscopic and analytical techniques including 1H-NMR, 13C-NMR, MS and elemental analysis. Compounds 5b and 5c experienced moderate activity against the urease producing Klebsiella pneumoniae strains better than the standard drug used chloramphenicol and less than the parent drug ciprofloxacin. On the other hand, most of the tested compounds showed a urease inhibitory activity more than the parent drug, ciprofloxacin and comparable to standard, thiourea. The docked compounds exhibited better binding to urease enzyme of H. pylori than standard, AHA with binding scores for correlate to the anti-urease assay results. Compound 5b was the most potent anti-Klebsiella pneumoniae urease inhibitor with activity higher the standard (IC50 = 67.8 and 78.89 µM, respectively).Minia UniversityJournal of Modern Research2636-39091120190701Exact Solutions For some nonlinear Partial Differential Equations by A Variation of (𝑮′𝑮⁄)-Expansion Method:8124136210.21608/jmr.2019.11763.1000ENA. R. ShehataDepartment of Mathematics, Faculty of Science, Minia University, 61519 Minia, EgyptF. Abdel BasserDepartment of Mathematics, Faculty of Science, Minia University, 61519 Minia, EgyptSafaa S.M.Abu-amraDepartment of Mathematics, Faculty of Science, Minia University, 61519 Minia, EgyptDepartment of Mathematics Faculty of Science, Omar Al-Mukhtar University, Al-Bayda. LibyaJournal Article20190410In this article , we study exact solutions of nonlinear of Burger’s Equation, Symmetric Regularized Long Wave (SRLW) equation, and Whitham-Broer-Kaup equations by using the variation of (G'⁄G)-expansion method, respectively. With the aid of mathematical software Maple, we can obtain the exact solutions for the above equations. Here we use the variation of (G'⁄G)-expansion method by applying it to solve the above mentioned equations, some new exact traveling wave solutions are obtained which include solitary wave solutions.When the arbitrary constants are taken some special values, the periodic and soliton solutions are obtained from the travelling wave solutions. The obtained solutions are new and not found elsewhere. It is shown that the methods are effective and can be used for many other nonlinear evolution equations (NLEEs) in mathematical physics. This methods is effectual, uncomplicated and can also be used to tackle a number of other differential equations related to mathematical physicsMinia UniversityJournal of Modern Research2636-39091120190701STUDYING THE INFLUENCE OF DIFFERENT COOLING TECHNIQUES ON PHOTOVOLTAIC-CELLS PERFORMANCE13184136310.21608/jmr.2019.12713.1002ENAhmed H.AliDepartment of mechanical engineering, Faculty of Engineering, Minia University, 61519 Minia, EgyptKhalid H. M.AbdalrahmanDepartment of mechanical engineering, Faculty of Engineering, Minia University, 61519 Minia, EgyptS. S.WahidDepartment of mechanical engineering, Faculty of Engineering, Minia University, 61519 Minia, EgyptJournal Article20190512The effect of temperature on the electrical parameters of photovoltaic cells is negative. The efficiency of photovoltaic cells can be enhanced by cooling which the temperature is considered as one of the main factors that affect negatively on the output power. This study was carried out to compare between three different cooling techniques and determine their effects on the output power. The first, cooling techniques is applied, the panel front surface cooled using the water spray on the surface. The second, the panel back surface cooled by extended fins. The third, the panel back surface cooled by extended fins with fans. As expected, the results of comparisons different methods using in cell cooling showed that, there is an increase in the efficiency of photovoltaic cells with the drop in cell temperature, which helps to increase the rate of photovoltaic cell performance and output power. In these experiments the output power increased 2.5%. At the first technique using water spray method the temperature dropped 7 degrees. At the other two methods the temperature dropped 3 degrees less than the panel without cooling. The used pump and fans were power consuming. So, the most effective method was cooling using the fins.Minia UniversityJournal of Modern Research2636-39091120190701Incorporating nano graphene oxide to poly-methyl methacrylate; antibacterial effect and thermal expansion.19234136410.21608/jmr.2019.14281.1003ENReem GamalDepartment of Biomaterials, Faculty of Dentistry, Minia University, 61519 Minia, Egypt0000-0002-2666-4118Yasser F.GomaaDepartment of Biomaterials, Faculty of Dentistry, Minia University, 61519 Minia, Egypt0000-0002-1024-3423Ashraf M.SaidDepartment of Bio-Medical Engineering, Faculty of Engineering, Minia University, 61519 Minia, EgyptJournal Article20190703Aim: This in vitro study was performed to evaluate antibacterial effect and thermal expansion of commercial available poly-methyl methacrylate (PMMA) incorporated by nano graphene oxide (GO) in different concentration. <br /> Method: Nano graphene oxide in five concentrations 0%, 0.05%, 0.1%, 0.15% and 1% by weight was incorporated to PMMA to form groups I-V respectively. To evaluate the antibacterial effect against Streptococcus Mutans, minimal inhibitory concentration (MIC) for GO dispersion was done and agar well diffusion test for groups I-IV was done. Thermal expansion was assessed through measuring the linear coefficient of thermal expansion.<br /> Results: For antibacterial effect, all concentrations tested for MIC showed inhibition zone varied from 0.5 to 2mm in diameter. All tested groups evaluated by agar well diffusion method showed no inhibition zones except for group II. Significant reduction in coefficient of thermal expansion was showed by increasing GO concentration.<br /> Conclusions: Incorporation of GO in to PMMA at concentration of 0.5% can inhibit the growth of Streptococcus Mutans. There is an inverse relation between the concentrations of GO and the coefficient of thermal expansion.