sayed, H., issa, M., mahmoud, M., ismail, H., darwish, A., abdelkader, E. (2022). Cytotoxic Activities of Cymbopogon citratus Extracts Three types of human cancer cell lines were tested: Lung Carcinoma (A549), Breast Cancer (MCF-7) and Hepatocellular Carcinoma (Hep G2). Journal of Modern Research, 4(1), 21-26. doi: 10.21608/jmr.2021.90284.1081
Heba sayed; mohammady issa; magda mahmoud; hamadi ismail; ahmed darwish; emad abdelkader. "Cytotoxic Activities of Cymbopogon citratus Extracts Three types of human cancer cell lines were tested: Lung Carcinoma (A549), Breast Cancer (MCF-7) and Hepatocellular Carcinoma (Hep G2)". Journal of Modern Research, 4, 1, 2022, 21-26. doi: 10.21608/jmr.2021.90284.1081
sayed, H., issa, M., mahmoud, M., ismail, H., darwish, A., abdelkader, E. (2022). 'Cytotoxic Activities of Cymbopogon citratus Extracts Three types of human cancer cell lines were tested: Lung Carcinoma (A549), Breast Cancer (MCF-7) and Hepatocellular Carcinoma (Hep G2)', Journal of Modern Research, 4(1), pp. 21-26. doi: 10.21608/jmr.2021.90284.1081
sayed, H., issa, M., mahmoud, M., ismail, H., darwish, A., abdelkader, E. Cytotoxic Activities of Cymbopogon citratus Extracts Three types of human cancer cell lines were tested: Lung Carcinoma (A549), Breast Cancer (MCF-7) and Hepatocellular Carcinoma (Hep G2). Journal of Modern Research, 2022; 4(1): 21-26. doi: 10.21608/jmr.2021.90284.1081
Cytotoxic Activities of Cymbopogon citratus Extracts Three types of human cancer cell lines were tested: Lung Carcinoma (A549), Breast Cancer (MCF-7) and Hepatocellular Carcinoma (Hep G2)
2Agric. Chem. Dept., Fuc. Of Agri. Minia Univ. Egypt.
3Central Lab of Organic Agriculture . Agri. Res. Center.
Abstract
Lemon grass is a tiny herbaceous plant in the Poaceae family known as Cymbopogon citratus. It is traditionally used to treat cancer, fever, sore throats, cough, laryngitis, bronchitis, body aches, headaches, and digestive problems, etc. The cytotoxic activity of Cymbopogon citratus Extracts Three types of human cancer cell lines were tested: Lung Carcinoma (A549), Breast Cancer (MCF-7) and Hepatocellular Carcinoma (Hep G2) are examined in this study. The plant material was chemically fractionated with ethanol 80 percent, ethyl acetate, and hexane, then tested for bioactivity. The maximum anticancer activity was found in ethyl acetate extract against A549, HepG2 , and MCF-7 human cancer cells with cell viability percentage (64.09±1.11 % , 41.22± 0.34% , and 66.24± 1.50%, respectively) with IC50 values (147, 65, and 155µg/ml, respectively). The findings demonstrate that the ethyl acetate fraction of Cymbopogon citratus is a rich source of phenolics and other chemicals that can help prevent cancer growth.
View on SCiNiTO
Top